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Multiple Choice

Which term describes variation in endothelial cell size?

Variation in endothelial cell size is known as polymegathism. In the corneal endothelium, cells normally remain fairly uniform in size and shape, often appearing hexagonal. When the endothelium is stressed or damaged, the sizes vary more widely (polymegathism) and the shapes can become irregular as well (pleomorphism). The other terms describe different ideas: endotheliopathy is a broad disease-related issue of the endothelium, and morphometry is the measurement of cell size and shape, not specifically the variation itself.

Variation in endothelial cell size is known as polymegathism. In the corneal endothelium, cells normally remain fairly uniform in size and shape, often appearing hexagonal. When the endothelium is stressed or damaged, the sizes vary more widely (polymegathism) and the shapes can become irregular as well (pleomorphism). The other terms describe different ideas: endotheliopathy is a broad disease-related issue of the endothelium, and morphometry is the measurement of cell size and shape, not specifically the variation itself.