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Multiple Choice

Which of the following events occurred earliest in corneal transplantation history?

The earliest event is the design of an artificial cornea in 1789. This shows an early attempt to replace the cornea with a synthetic substitute before any instrument specifically enabling corneal work (like a trephine), before animal cornea experiments, and long before the first successful human corneal transplant in 1905. The timeline then progresses to the trephine concept in 1797, animal cornea work in 1824, and finally the first successful human graft in 1905. So, the 1789 artificial cornea design is the first milestone among the listed events.

The earliest event is the design of an artificial cornea in 1789. This shows an early attempt to replace the cornea with a synthetic substitute before any instrument specifically enabling corneal work (like a trephine), before animal cornea experiments, and long before the first successful human corneal transplant in 1905. The timeline then progresses to the trephine concept in 1797, animal cornea work in 1824, and finally the first successful human graft in 1905. So, the 1789 artificial cornea design is the first milestone among the listed events.