What does the term "in-situ" mean in eye banking?

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What does the term "in-situ" mean in eye banking?

In-situ means the corneal tissue is taken from the donor while the eye remains in its socket. So, the corneo-scleral rim is removed with the globe still in place—the cornea with a surrounding scleral rim is excised, but the rest of the eyeball stays in the orbit. This method contrasts with removing the entire globe (enucleation) or removing the rim after the globe has been removed, which are not in-situ approaches. The idea of preserving only the corneal endothelium isn’t about how the tissue is harvested, but about what tissue is kept, so it doesn’t define in-situ procurement.

In-situ means the corneal tissue is taken from the donor while the eye remains in its socket. So, the corneo-scleral rim is removed with the globe still in place—the cornea with a surrounding scleral rim is excised, but the rest of the eyeball stays in the orbit. This method contrasts with removing the entire globe (enucleation) or removing the rim after the globe has been removed, which are not in-situ approaches. The idea of preserving only the corneal endothelium isn’t about how the tissue is harvested, but about what tissue is kept, so it doesn’t define in-situ procurement.

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