Under PKP, corneas from patients with prior anterior segment surgery may be used if what condition is met?

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Multiple Choice

Under PKP, corneas from patients with prior anterior segment surgery may be used if what condition is met?

Endothelial cell health is what matters for a PKP graft. The corneal endothelium is the layer that keeps the cornea clear by pumping fluid out of the stroma; if its cells are too few or damaged, edema and graft failure can occur. Even if the donor had anterior segment surgery in the past, the tissue can be used as long as the endothelial cell density meets the eye bank’s endothelium standard. Eye banks assess this with specular microscopy to ensure there are enough healthy endothelial cells to support a successful transplant. If the endothelial count is adequate, the cornea is considered suitable despite previous surgery. Age, glaucoma history, or regional origin aren’t the deciding factors here; endothelial health is.

Endothelial cell health is what matters for a PKP graft. The corneal endothelium is the layer that keeps the cornea clear by pumping fluid out of the stroma; if its cells are too few or damaged, edema and graft failure can occur. Even if the donor had anterior segment surgery in the past, the tissue can be used as long as the endothelial cell density meets the eye bank’s endothelium standard. Eye banks assess this with specular microscopy to ensure there are enough healthy endothelial cells to support a successful transplant. If the endothelial count is adequate, the cornea is considered suitable despite previous surgery. Age, glaucoma history, or regional origin aren’t the deciding factors here; endothelial health is.

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