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Multiple Choice

Keratic precipitates are accumulations of white blood cells on which ocular surface layer?

Keratatic precipitates are inflammatory cell clusters that settle on the posterior surface of the cornea, specifically the corneal endothelium. Inflammation in the front part of the eye (anterior uveitis) disrupts the blood-aqueous barrier, allowing white blood cells to reach the endothelial surface, where they accumulate as these deposits. They appear as white or gray spots on the inner side of the cornea and are detected during slit-lamp examination. They’re not on the corneal epithelium, nor on the sclera or conjunctiva, which lie in front of or separate from the endothelial layer. The endothelium is the innermost corneal layer, and deposition there reflects intraocular inflammatory activity. Larger, greasy-appearing precipitates can occur in granulomatous uveitis (mutton-fat KPs), while smaller ones are typical of non-granulomatous cases.

Keratatic precipitates are inflammatory cell clusters that settle on the posterior surface of the cornea, specifically the corneal endothelium. Inflammation in the front part of the eye (anterior uveitis) disrupts the blood-aqueous barrier, allowing white blood cells to reach the endothelial surface, where they accumulate as these deposits. They appear as white or gray spots on the inner side of the cornea and are detected during slit-lamp examination. They’re not on the corneal epithelium, nor on the sclera or conjunctiva, which lie in front of or separate from the endothelial layer. The endothelium is the innermost corneal layer, and deposition there reflects intraocular inflammatory activity. Larger, greasy-appearing precipitates can occur in granulomatous uveitis (mutton-fat KPs), while smaller ones are typical of non-granulomatous cases.