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Multiple Choice

In 1935, which surgeon used cadaveric corneas stored at 2-4 degrees and donors screened for infections?

The main idea is how corneal grafts began to be stored and made safer for transplantation. Vladimir Filatov in 1935 described using cadaveric corneas stored at cold temperatures (about 2–4°C) and screening donors for infections. This approach extended the viability window for corneal tissue outside the body and reduced the risk of transmitting infections, making keratoplasties more feasible and safer. Earlier work, such as Eduard Zirm’s first successful transplant in 1905, used fresh donor tissue rather than stored tissue, so it didn’t involve this cold-storage and donor-screening method. Filatov’s method represents a key step in moving from immediate, fresh grafts to preserved tissue that could be matched and transplanted with greater safety.

The main idea is how corneal grafts began to be stored and made safer for transplantation. Vladimir Filatov in 1935 described using cadaveric corneas stored at cold temperatures (about 2–4°C) and screening donors for infections. This approach extended the viability window for corneal tissue outside the body and reduced the risk of transmitting infections, making keratoplasties more feasible and safer. Earlier work, such as Eduard Zirm’s first successful transplant in 1905, used fresh donor tissue rather than stored tissue, so it didn’t involve this cold-storage and donor-screening method. Filatov’s method represents a key step in moving from immediate, fresh grafts to preserved tissue that could be matched and transplanted with greater safety.